Neohesperidin Dihydrochalcone(NHDC) Sweetener
Specification: >98% (HPLC)
Appearance: White or light yellow crystal powder
CAS No.: 20702-77-6
Molecular Formula: C28H36O15
Molecular Weight: 612.58 g/mol
Melting Point: 152-154 ℃
What’s Neohesperidin Dihydrochalcone(NHDC)?
Neohesperidin Dihydrochalcone(NHDC), also known by its E number E959, is a non-nutritive (essentially zero-calorie), high-intensity artificial sweetener derived from natural citrus extract neo-hesperidin in pure water by hydrogenation reaction. NHDC is 1500-1800 times sweeter than sucrose and can be used as a low-energy food sweetener for diabetics. And it is refreshing and pleasant, accompanied by a refreshing sensation of mint and a special fragrance.
NHDC has good stability, very stable in the PH range of 2-14. It is one of the most stable and safe sweeteners known at present, commonly used as a flavor enhancer and bitterness masking agent in food and beverages. It has a strong synergistic effect, which can increase sweetness, reduce the amount of sweeteners, and reduce costs. It can be used in combination with sucralose, polyol sweeteners, saccharin, etc. It also has antioxidant, anti-inflammatory, and skin-whitening effects. When used in animal feed, it can improve animal appetite and promote growth.
Applications of Neohesperidin Dihydrochalcone(NHDC)?
Sweetness
NHDC can synergize strongly with many other high-intensity sweeteners, allowing reduction of total sweetener load.
Flavor enhancer
NHDC has strong taste-potentiating and flavor-modifying effects — it enhances mouthfeel, masks bitterness, and boosts certain flavor notes (especially in fruit, mint, and dairy flavors).
Bitter masking
NHDC has excellent bitter-masking ability, has been widely used to cover quinine, caffeine, herbal extract, or protein bitterness.
Antioxidant/anti-inflammatory/whitening
NHDC belongs to flavonoid derivatives, which have strong antioxidant properties and can act as antioxidants in food. It can be used in toothpaste, mouthwash, etc.
Animal feed
NHDC can be used in combination with neotame saccharin sodium in feed, which can well cover the bitterness and metallic taste of saccharin sodium, greatly improve the sweetness, thereby saving costs.
About the supplier
Xi’an Rainbow Biotech Co., Ltd is a professional bulk supplier and manufacturer of Neohesperidin Dihydrochalcone sweetener powder. Our NHDC is made from bitter orange (Citrus aurantium) extract neo-hesperidin in pure water by hydrogenation reaction. The chemical modification (adding hydrogen across a double bond and opening the chalcone ring) dramatically changes its taste from intensely bitter to very sweet. The solvent used in the whole preparation process is pure water, which is safe and non-toxic, without any chemical residues.








